Does CBD Oil Make You Hungry?

The therapeutic potential of Cannabidiol (CBD) has been the subject of extensive scientific research and is increasingly recognized for its myriad health benefits. However, a question that frequently arises is whether CBD oil can induce hunger. Many individuals are keen on understanding this aspect for a variety of reasons; some seek to boost their appetite for weight gain or medical requirements, while others fear unwelcome weight increases as a side effect.

Understanding the impact of CBD oil on appetite necessitates an exploration into its biochemical interactions with our body, especially in comparison with Tetrahydrocannabinol (THC), another prominent compound found in Cannabis Sativa plants. Both of these compounds interact differently with the endocannabinoid system within human bodies, leading to distinct physiological responses.

An evidence-based assessment will further elucidate not only the effect on appetite but also how CBD could possibly aid weight loss and fitness goals. This article aims to provide comprehensive insights into these aspects based on the scientific literature available to date.


  • CBD oil does not stimulate hunger like THC.
  • CBD may restore a healthy appetite by easing nausea, reducing anxiety, and alleviating inflammation.
  • CBD oil’s anti-inflammatory properties can reduce gut inflammation, leading to better digestion and nutrient absorption, indirectly increasing appetite.
  • CBD oil can relieve nausea, making food more appealing and potentially increasing food intake.

Does CBD Make You Hungry?

Contrary to common assumptions, CBD oil does not necessarily stimulate hunger in the same way as THC; rather, it may restore a healthy appetite through various mechanisms such as easing nausea, reducing anxiety, and alleviating inflammation.

Both CBD and THC are cannabinoids found in the cannabis plant, with varying effects on the human body. However, while THC interacts directly with cannabinoid receptors in the brain to trigger an increase in appetite commonly known as ‘the munchies’, CBD works differently.

Instead of stimulating hunger directly, CBD oil can potentially influence other factors that contribute to appetite, such as mood and digestive comfort.

Research suggests that CBD oil’s anti-inflammatory properties can help reduce gut inflammation, which often leads to discomfort or a loss of appetite. By reducing inflammation in the digestive tract, it may create a more comfortable environment for digestion and nutrient absorption, thereby indirectly leading to an increase in appetite.

By easing anxiety, which is often a significant factor contributing to reduced food intake or eating disorders such as anorexia nervosa, CBD oil could support balanced eating behavior.

Furthermore, its ability to relieve nausea, whether due to medication side effects or conditions like gastritis, can also encourage healthier dietary habits by making food more appealing.

Therefore, while CBD oil doesn’t cause hunger per se like THC does, its overall positive effects on wellbeing could certainly promote a healthier relationship with food.


Diving into the complex world of cannabinoids, one must differentiate between CBD and THC, two primary compounds found in cannabis that interact distinctly with the endocannabinoid system, influencing various bodily functions, including appetite regulation. The first compound, cannabidiol (CBD), is primarily derived from industrial hemp and is non-intoxicating. CBD interacts with cannabinoid receptors in the body but does not bind directly to them, instead influencing their activity indirectly. This interaction contributes to a variety of effects, such as pain reduction and anxiety relief; however, it does not significantly stimulate appetite or enhance the sense of smell.

In contrast, tetrahydrocannabinol (THC) is responsible for the psychoactive effects associated with marijuana use due to its direct binding with cannabinoid receptors. When THC binds to these receptors in areas of our brain that control feelings of hunger and our sense of smell, it can increase both appetite stimulation and food enjoyment, a phenomenon commonly known as ‘the munchies’. In terms of chemical composition, while both CBD and THC share a similar molecular structure consisting of 21 carbon atoms, 30 hydrogen atoms, and 2 oxygen atoms, their atomic arrangements differ, resulting in distinct interactions within our bodies.


Cannabinoid Source Interaction with Cannabinoid Receptors Impact on Appetite
CBD (Cannabidiol) Industrial Hemp Indirect Influence No Significant Appetite Stimulation
THC (Tetrahydrocannabinol) Marijuana Direct Binding Increases Appetite Stimulation


How CBD and THC Affect the Appetite

Exploring the influence of cannabinoids on appetite, one can understand that CBD and THC interact uniquely with the endocannabinoid system, a complex cell-signalling system that plays a critical role in regulating numerous physiological processes, including hunger.

The endogenous cannabinoid system is primarily composed of two types of receptors: CB1 and CB2. Notably, THC directly stimulates the CB1 receptor, which is known to be largely responsible for promoting appetite. Conversely, CBD does not directly stimulate this receptor but instead tends to suppress appetite by antagonizing CB1 receptors.

The different effects on hunger can also be attributed to their interaction with appetite hormones such as ghrelin. It has been established that THC stimulates hunger through its interaction with ghrelin, an important hormone that triggers feelings of hunger. On the other hand, CBD oil does not have this same effect due to its ability to antagonize the cannabinoid receptor type 1 (CB1).

Thus, while both compounds interact with the endocannabinoid system and play roles in affecting appetite regulation, they do so in unique ways, leading to different impacts on whether or not one feels hungry.

Can You Take CBD to Boost Your Appetite?

In the realm of cannabinoid research, there is growing evidence that Cannabidiol (CBD) may have potential utility in enhancing appetite.

A critical review of studies indicates that CBD’s anti-nausea effects can potentially contribute to an increased desire for food intake.

Furthermore, it has been suggested that improvements in gastrointestinal health due to CBD administration could further stimulate appetite, thus warranting further exploration into this therapeutic avenue.

CBD alleviates nausea and boosts appetite.

Much like a gentle nudge to a stalled engine, CBD oil works to alleviate nausea, thereby stimulating appetite by activating serotonin receptors in the brain. This process is pivotal in managing symptoms of nausea, which often stem from various causes such as gastrointestinal issues, pregnancy, chemotherapy, and medication side effects, among others. Nausea can have detrimental impacts on a person’s health due to reduced food intake, leading to malnutrition or weight loss. Therefore, CBD’s role as an appetite stimulant comes into play through its ability to diminish these feelings of nausea.

Research has shown that CBD interacts with the endocannabinoid system (ECS), which plays a significant role in regulating our feeding behavior and hence impacting our appetite. The ECS essentially modulates the release of certain neurotransmitters, including serotonin, which, when activated, reduces feelings of nausea and subsequently stimulates hunger. Furthermore, CBD is known for its anti-anxiety and stress-alleviating properties, both of which are common underlying causes of mild-to-moderate nausea.

Studies demonstrating how CBD activates serotonin receptors:

A study published in the British Journal of Pharmacology found that CBD could reduce vomiting and nausea-like behavior via indirect agonism of 5-HT (1A) somatodendritic autoreceptors located in the dorsal raphe nucleus.

Another study conducted by the RINCK Research Institute indicated that there was a significant decrease in subjective anxiety following administration of CBD, partly due to its effect on activity within the limbic and paralimbic regions.

In conclusion, it becomes clear that while CBD does not directly make you feel hungry, it manages several physiological processes, such as alleviating nausea or reducing stress levels, that ultimately lead to feeling an increased sense of hunger, thus serving as an effective appetite stimulant.

CBD improves gastrointestinal health and stimulates appetite.

Beyond the realm of nausea alleviation, CBD’s significant benefits extend to improving gastrointestinal health, thereby playing a crucial role in appetite stimulation. This improvement in gastrointestinal health is achieved primarily through the interaction between CBD and GPR55 receptors. By agonistizing these receptors, CBD effectively inhibits inflammation within the gut. Inflammation often leads to a loss of appetite or changes in how food is processed within the body; hence, its reduction significantly bolsters one’s hunger and desire for food.

Moreover, this interaction between CBD and GPR55 receptors also activates enteric glial cells. These specialized cells are instrumental in maintaining gut homeostasis and protecting against harmful substances ingested with food. Besides, they play a critical role in enhancing communication within the nervous system surrounding our digestive tract, which ultimately can stimulate appetite. Furthermore, studies have revealed that PPAR mediates these beneficial anti-inflammatory effects brought about by CBD oil use, thereby promoting overall gastrointestinal health.

In conclusion, while further research is needed to fully understand all mechanisms involved, it’s evident that CBD oil has potential benefits for gastrointestinal health and can make you feel hungrier by reducing inflammation and activating certain cellular responses conducive to stimulating your appetite.

Can CBD Oil Help You Lose Weight?

Transitioning from the exploration of CBD’s potential role in appetite stimulation, we now pivot to investigate its possible impact on weight loss.

The current discourse revolves around the hypothesis that CBD may foster weight reduction by converting white fat into brown fat, amplifying metabolic rates, and curbing food consumption.

Furthermore, it is also postulated that CBD could be instrumental in regulating insulin levels, thereby contributing to a balanced body mass index.

CBD converts white fat into brown fat.

Intriguingly, research suggests that CBD can contribute to the transformation of white fat into brown fat, a process with potential implications for weight loss and overall metabolism. White fat is the predominant form stored in our bodies and contributes to the storage of excess calories. In contrast, brown fat is responsible for burning energy and generating body heat, thus promoting calorie expenditure instead of storage.

When CBD interacts with CB1 receptors found in our bodies’ endocannabinoid system, it appears to stimulate this conversion from white to brown fat cells. The metabolic effects induced by this conversion offer several health benefits, including increased energy expenditure, improved insulin sensitivity, and a potentially reduced risk of obesity-related disorders such as type 2 diabetes and heart disease.

Some key findings from cannabinoid research include:

1. A study published in Molecular Metabolism found that CBD induces the browning’ of white adipocytes (fat cells), leading to an increase in their thermogenic capacity.

2. Another study conducted on rats showed that chronic CBD administration led to significant reductions in body weight.

3. Research has also shown that blocking CB1 receptors increases the activity of genes involved in producing brown fat.

4. Lastly, a review article published in Cannabis and Cannabinoid Research highlights that modulation of CB1 receptors influences food intake; however, rather than making you feel ‘hungry’, it might actually suppress appetite.

In conclusion, while more research is needed, particularly human trials, these findings suggest promising possibilities for using CBD oil as part of a holistic approach towards managing body weight and metabolic health.

CBD could increase your metabolism and reduce food consumption.

Preliminary research proposes that CBD may play an impactful role in enhancing metabolic rates and decreasing food consumption.

In animal studies, CBD has been shown to interact with cannabinoid receptors, specifically CB1 and CB2 receptors located within the central nervous system and peripheral tissues, respectively.

These interactions have been linked to the regulation of metabolic functions and a decrease in appetite.

This intriguing discovery suggests that CBD could potentially act as an effective appetite suppressant, reducing food intake by influencing neuronal and hormonal mechanisms.

The potential weight-reducing benefits of CBD appear promising but are still under investigation.

It is believed that by modulating the function of these cannabinoid receptors, CBD oil might enhance metabolism efficiency, leading to increased energy expenditure even at rest.

This enhancement of metabolic activity, along with the possible reduction in food consumption, could pave the way for new therapeutic strategies for treating obesity.

However, further detailed research is required to fully understand the implications of these findings on human health and disease management.

CBD regulates insulin levels.

Transitioning from the exploration of CBD’s potential effects on metabolism and reduced food consumption, it is pertinent to delve into a related aspect of cannabinoid influence: the regulation of insulin levels. The link between CBD oil and hunger could be further elucidated by examining this regulatory function in detail.

Scientific evidence suggests that CBD has a significant role in regulating insulin levels, which indirectly influence appetite suppression and body mass. Preclinical research on non-obese diabetes-prone mice demonstrated that when treated with cannabidiol (CBD), only 30% developed diabetes compared to an untreated control group where 86% became diabetic. This highlights the protective effect CBD may have against the development of diabetes, possibly through its interaction with CB1 and CB2 receptors, which are known to play crucial roles in metabolic processes, including hunger management. These receptors are key components of the endocannabinoid system, impacting energy levels as well as glucose homeostasis; hence, their modulation by cannabinoids like CBD can affect overall metabolic health, including insulin sensitivity.

Furthermore, studies suggest that by influencing these receptors, particularly CB1 receptor antagonism, CBD may promote weight loss by reducing appetite and increasing metabolism. This insight underscores another possible mechanism by which the use of CBD oil might not necessarily make you feel hungry but instead assist in maintaining optimal energy balance within your body.

Therefore, while more research is needed to fully understand the complexities involved, current indications point towards the potential for CBD to contribute positively to metabolic health and weight management.

Can CBD Oil Help Me Achieve My Fitness Goals?

Despite the common misconception that CBD oil might stimulate appetite and thus derail one’s fitness goals, research suggests it can actually function as a potent ally in achieving those objectives.

Studies have shown that while THC, another component found in cannabis, may stimulate appetite, CBD does not have this same effect. Instead, CBD oil may assist with weight loss by helping to regulate insulin levels and control hunger cues.

1. Regulation of Hunger: Contrary to popular belief, CBD oil does not necessarily induce hunger. In fact, it has been suggested that the use of CBD could potentially reduce food intake and boost metabolism, which can contribute to weight loss and help individuals meet their fitness goals.

2. Boosting Energy Levels: Some research also indicates that using CBD as part of a daily routine might help increase energy levels throughout the day due to its potential role in regulating blood sugar levels. This increased energy can be beneficial when trying to maintain an exercise routine or other physical activity.

3. Recovery Assistance: Furthermore, it is believed that incorporating CBD oil into post-workout routines may aid recovery by reducing inflammation and pain-related symptoms following strenuous exercise.

In essence, careful incorporation of CBD oil into a daily health regimen could offer several benefits for individuals striving toward specific fitness goals. However, further research is necessary before definitive conclusions about these potential benefits can be drawn.


In conclusion, research indicates that CBD oil does not inherently stimulate hunger like its counterpart, THC. Instead, it influences the body’s endocannabinoid system to potentially improve mental health and metabolic functions. These improvements may indirectly enhance appetite or contribute to weight loss through improved overall well-being.

Like a dual-edged sword, CBD oil can serve both those endeavoring to increase their appetite for medical reasons and individuals seeking aid in weight management or fitness goals. The efficacy of this compound underscores the complexity and versatility of the human body’s response to cannabinoids.


Research on the effects of CBD on appetite and hunger is limited. Some studies have suggested that CBD may increase appetite, while others have found that it can suppress it. However, there is no conclusive evidence that CBD makes you hungry.

There is no evidence to suggest that CBD can directly cause weight gain. Some studies have shown that CBD may increase appetite, which could potentially lead to weight gain if not balanced with a healthy diet and exercise routine. It is important to note that CBD should not be used as a substitute for traditional weight gain treatments.

Some studies have suggested that CBD may increase appetite, but this effect has not been consistently observed. It is important to note that individual responses to CBD may vary and more research is needed to fully understand the effects of CBD on appetite.

CBD interacts with the endocannabinoid system, which helps regulate various bodily functions, including appetite. While research is ongoing, some studies have shown that CBD may help regulate appetite by binding to certain receptors in the endocannabinoid system.

The “munchies,” or an increased desire to eat, is commonly associated with THC consumption. CBD is a non-intoxicating compound that does not produce the same psychoactive effects as THC. While some studies suggest that CBD may increase appetite, it is unlikely to cause the same intense cravings as THC.

While some studies suggest that CBD may help regulate appetite, there is no evidence to suggest that CBD can directly promote weight loss. It is important to approach weight loss holistically, with a focus on exercise and a healthy diet.

Some studies have suggested that CBD may help suppress the appetite, but more research is needed to understand this effect fully.

Some studies have suggested that CBD may help suppress the appetite, but individual responses to CBD may vary. It is important to maintain a balanced diet and exercise routine when using CBD to regulate appetite.

Some studies have shown that CBD may help reduce appetite, but more research is needed to fully understand this effect.

The best way to take CBD oil for appetite regulation may depend on individual needs and preferences. Some people prefer to take CBD orally, while others prefer topical applications. It is important to start with a low dosage and gradually increase as needed, under the guidance of a healthcare professional.


Rock, E. M., et al. “Cannabidiol, a non‐psychotropic component of cannabis, attenuates vomiting and nausea‐like behaviour via indirect agonism of 5‐HT1A somatodendritic autoreceptors in the dorsal raphe nucleus.” British journal of pharmacology 165.8 (2012): 2620-2634. [PDF]

Kirkham, Tim C. “Cannabinoids and appetite: food craving and food pleasure.” International Review of Psychiatry 21.2 (2009): 163-171. [PDF]

Farokhnia, Mehdi, et al. “Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study.” Translational psychiatry10.1 (2020): 1-11. [HTML]

Roberts, Carl A., et al. “Exploring the munchies: An online survey of users’ experiences of cannabis effects on appetite and the development of a Cannabinoid Eating Experience Questionnaire.” Journal of Psychopharmacology 33.9 (2019): 1149-1159. [DOC]

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